Gangrene is characterized by acute, sudden pain or numbness in a lower extremity, which may be accompanied by skin that feels cold and looks darker than usual. Wet gangrene shows signs of tissue decay; redness, oozing, swelling, and foul odor at the site may be present.
It is important that gangrene areas are removed surgically to prevent infection that can move quickly throughout the body and cause death. If gangrene is suspected, seek immediate medical help.